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Demystifying the Art of Research Commercialisation with a Spin-out Simulation

November 25, 2024

“It is easy to understand why it is difficult to win in a game where there will be a loser at the end. But we were playing a game where everyone can come out winning. So why is it still so hard to play?”

— Prof Tom Stace, Co-founder and CEO of Analog Quantum Circuits.

Spinning-out a company from a university is no small feat. It’s often described as an art because it rarely happens smoothly or easily. This is due to the various assumptions we make, the conflicting drivers we each bring to the table, and the different processes we all follow to get these deals across the line. Everyone — researchers, venture capitalists (VCs), tech transfer offices (TTOs) — has their own priorities, making negotiations challenging.

Researchers often come to the table expected to understand everyone else’s jargon and technical language which can complicate and slow the process. They are asked to upskill on the go, often feeling on the back foot throughout negotiations. To help remove this barrier, we’re working on a vocabulary guide that will be published in the coming months. This resource aims to bridge communication gaps and make the process more straightforward for researchers.

TTOs, meanwhile, often find themselves portrayed as the "villains at worst, middle-men at best” in these negotiations. The truth is that they want to reach reasonable decisions, but they have complex bureaucratic and policy frameworks they can’t work outside processes to navigate. Commercialisation often represents just a tiny fraction of the university’s overall funding, making it difficult for senior management to prioritise. TTO teams are passionate about innovation but are limited by the policy frameworks within the university system. 

On the other side, VCs can be seen as sharks or the devil — greedy, impatient — how hard can it be once the invention has been created!? VCs have their own set of principles for investment. This is because they have made a commitment to their LPs to return their capital and then some! These principles differ from fund to fund and investor to investor. They are not always immediately apparent to others in the process, leading to further confusion. 

Why, despite having the shared goal of commercialising research, do we still face confusion, delays, and frustration? This very question sparked the development of our ‘Spin-out Simulation.’

When entering negotiations to spin-out a company, having all stakeholders in the room is key. This helps ensure everyone is clear on each party’s needs to get the deal done while balancing the interests of future spin-outs.

This lesson became even clearer through a research commercialisation wargame we’ve developed and played twice now. The game highlights how quickly negotiations become adversarial due to conflicting goals. Despite knowing that time kills deals, we still struggle to spin-out opportunities quickly without overwhelming researchers or exhausting stakeholders.

Originally, our simulation aimed to find better ways to spin-out research from universities. What we discovered was that the game allows players to understand how each stakeholder thinks. For example, valuation is an issue that seems straightforward but is actually viewed differently by different stakeholders. Some VCs focus on securing a specific ownership stake and the quantum of capital needed and the stage the company is at defines the valuation, while TTOs often emphasise the value of the research and resources already invested and that drives how they define valuation of the company and their contribution. They can lead to very very different valuation expectations. These conflicting approaches can extend negotiations, but by understanding each other’s value drivers, we can move forward more efficiently.

Some other observations on varying approaches from stakeholders are below: 

Topic Researcher TTO VC
Resourcing Researchers looking to spin-out a startup often take a cautious approach to resourcing. They aim to maintain their university position to fulfil current obligations and protect their tenure, as it's difficult to re-enter academia once they leave. PhD students, however, are typically more willing to transition into the startup full-time. The TTO (Technology Transfer Office) accounts for potential issues like lost teaching hours, conflicts of interest, and the impact on the university when key staff leave to pursue a spin-out. Balancing the university?s interests with supporting the startup is a core challenge for the TTO. VCs prefer a team fully committed to the startup. A part-time founding team signals a lack of focus, which VCs view as a higher risk. They often encourage full-time involvement. VCs see particular value in PhD students who have been hands-on with the research and are willing to dedicate themselves fully to the startup.
Future Funding Researchers in the spin-out process often focus heavily on the immediate funding round, without considering long-term funding needs, staff incentivization, and the impact of future capital requirements on dilution. This short-term focus can lead to challenges as the startup grows and requires additional funding. The TTO typically concentrates on the initial and final stages of the spin-out process, with less focus on interim funding needs. They mainly consider the IP assignment and the amount raised at the beginning, ensuring that this funding facilitates the spin-out. However, ongoing funding requirements beyond this stage are often underemphasized. VCs are highly concerned with both current and future funding rounds. They assess how future rounds will affect both the founder?s stake and their own. This forward-looking approach influences how VCs negotiate each round, as they need to account for potential dilution and capital requirements needed for growth and scale over time.
Equity The hierarchical structure of academia can influence equity or commercialisation returns distribution. Professors often secure significant equity or share of the returns even if they are unlikely to take full-time roles in the startup, whereas PhD students, who are more likely to be full-time, may receive less. There is a debate over whether part-time contributors deserve as much equity upfront given their limited ongoing role ? although we have noticed that equity is often allocated fairly towards key team members. Depending on the university, there may be restrictions on founders holding equity. TTOs focus on protecting the university's interests, which can sometimes lead to losing sight of ensuring the researchers are incentivised to drive the startup's success and generate returns. VCs strongly prioritise incentivizing full-time team members, who are essential for driving the company forward. They are generally averse to fractional team members receiving large equity portions based on academic positions rather than their ongoing contributions. VCs also consider the dilutionary effects of capital and IP contributions on the founding team?s equity. Additionally, having a University hold significant shareholding can be a disincentive because they are large institutions that take longer times to effect decisions, and can influence access to R&D Tax incentives.

Here are some insights from those who’ve participated in the game so far:

“The more we can do to come together and understand everyone’s expectations and perspectives, the better we will be as a community creating impact. Communication is key!”

— Dr Erin Rayment,  Chief Commercialisation and Development Officer at Queensland University of Technology. 

“As government observers, it was a good exercise to demonstrate gaps and consider what role the government can play in this scenario, either directly or indirectly.”

— Amanda Russel, Associate Manager, Quantum and Advanced Technologies Science Development and Office of the Queensland Chief Scientist

We hope to bring this Spin-out Simulation to all states over the coming year. If you’re interested in co-hosting or participating, please reach out!

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